Reaction of phenolic mannich bases with enamines. General synthesis of pyran‐containing fused ring systems
- 1 December 1970
- journal article
- research article
- Published by Wiley in Journal of Heterocyclic Chemistry
- Vol. 7 (6) , 1311-1319
- https://doi.org/10.1002/jhet.5570070613
Abstract
The reaction of o‐phenolic Mannich bases with enamines yields cyclic O,N‐acetals having a 2‐aminodihydropyran or a spiropyranopiperidine structure in common. The 2‐aminodihydro‐pyrans are easily converted to 2‐hydroxydihydropyrans and to pyrans. The preparation of a large variety of pyran‐containing fused ring systems is reported.Keywords
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