Diurnal Variation in Retinal Thickening Measurement by Optical Coherence Tomography in Center-Involved Diabetic Macular Edema

Open Access
Publisher Website
Google Scholar
Abstract
Optical coherence tomography (OCT) is a noninvasive method for measuring the thickness of the central retina. It has become a standard tool in the management of patients with diabetic macular edema (DME). This imaging technique uses low-coherence interferometry to produce cross-sectional tomograms of the posterior segment eye structures. An 850-nm diode laser is used to measure the delay in light backscattering from different layers in the retina from which the retinal thickness is calculated. Retinal thickness is determined from multiple individual axial scans arrayed in a radial pattern along each of 6 linear segments all intersecting at the center. A computer algorithm is used to determine the inner and outer retinal boundaries for each scan.