ISOLATION AND PARTIAL CHARACTERIZATION OF BASEMENT MEMBRANE-LIKE COLLAGENS FROM BOVINE THORACIC AORTA
- 1 January 1980
- journal article
- research article
- Vol. 7 (4) , 262-280
Abstract
Collagen polymorphism was investigated in the bovine thoracic aortic media after extraction by a technique involving reduction of disulfide bonds followed by limited pepsin digestion. Type I, III, IV and V collagens were all fractionated from each other in the native state by differential salt precipitation both in acidic and neutral conditions. Type IV and V collagen were similar, if not identical, to the same collagens isolated from other tissues. The Type IV collagen fraction clearly contained 2 different .alpha.-sized components. The possible function of the different collagen types in aortic structure is briefly discussed.This publication has 30 references indexed in Scilit:
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