INVITRO AND INVIVO TRANSFER OF DRUG-RESISTANCE FOR SALMONELLA AND ESCHERICHIA-COLI STRAINS IN TURKEYS

  • 1 January 1976
    • journal article
    • research article
    • Vol. 37  (4) , 433-437
Abstract
In vitro and in vivo transfers of antibiotic drug resistance were observed when isolates of multi-resistant S. saint-paul and E. coli donors were mated with multi-sensitive E. coli and S. typhimurium recipients, respectively. For in vivo studies, day-old turkey poults were used. Drug resistances were transferred either alone on in various combinations. In vitro, transfer was more frequent from E. coli to S. typhimurium; in vivo, transfer was more often observed from S. saint-paul to E. coli. Transfer occurred in vivo within 3 or 6 days after the recipient strain was given to poults previously infected with donor bacteria. In some instances, phage typing of S. typhimurium indicated a change after transfer of drug resistance from E. coli to S. typhimurium. The criteria for in vivo transfer of drug resistance were discussed and the implications of a change in phage type were noted.