Evidence that at “high” extracellular methotrexate concentrations the transport barrier is unlikely to be an important mechanism of drug resistance
- 15 January 1982
- journal article
- research article
- Published by Elsevier in Biochemical Pharmacology
- Vol. 31 (2) , 263-266
- https://doi.org/10.1016/0006-2952(82)90223-4
Abstract
No abstract availableThis publication has 5 references indexed in Scilit:
- A methotrexate insensitive variant of folate reductase present in two lines of methotrexate-resistant L5178Y cellsPublished by Elsevier ,1980
- Methotrexate: clinical pharmacology, current status and therapeutic guidelinesCancer Treatment Reviews, 1977
- Impaired responsiveness to folinic acid protection in methotrexate-resistant L5178Y cellsPublished by Elsevier ,1975
- Methotrexate toxicity: Correlation with duration of administration, plasma levels, dose and excretion patternPublished by Elsevier ,1972
- SITES OF ACTION OF AMETHOPTERIN: INTRINSIC AND ACQUIRED DRUG RESISTANCEAnnals of the New York Academy of Sciences, 1971