Abstract
Persons (45) severely bitten by rabid dogs and wolves in Iran were treated after exposure with a new rabies vaccine produced in cultures of human diploid cells. All except 1 also received 1 injection of rabies immune serum. This treatment, in contrast to past experience with other vaccines, resulted in protection of all individuals against rabies. Almost a century after the postexposure treatment of humans was initiated, an effective tool for protecting man against rabies was developed.

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