Demonstration of human papillomavirus types 6 and 11 in juvenile laryngeal papillomatosis by in‐situ DNA hybridization
- 1 November 1987
- journal article
- research article
- Published by Wiley in The Journal of Pathology
- Vol. 153 (3) , 245-248
- https://doi.org/10.1002/path.1711530308
Abstract
A study is reported in which an in situ hybridization technique for the demonstration of human papillomavirus (HPV) employing a biotin–streptavidin polyalkaline phosphatase complex has been successfully applied to formalin‐fixed paraffin‐processed tissue obtained from ten patients with juvenile laryngeal papillomatosis. In all cases, positive results were obtained for either HPV type 6 or 11. Normal vocal cord epithelium was negative.Keywords
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