Stereotaxic amygdalotomy for epilepsy with aggressive behavior

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Abstract
Stereotaxic amygdalotomy was used to treat 25 patients for behavioral abnormalities, epilepsy, and depression between Aug. 28, 1963, and July 27, 1964. Behavioral abnormalities were eliminated in seven of 20 patients and markedly improved in nine others. Convulsions were eliminated in four of 21 patients and improved in 12. Stereotaxic amygdalotomy produced overall improvement in 23 of 25 patients. Two of 12 patients committed to mental institutions have been released. Five of eight patients whose commitment to mental institutions was impending have improved after amygdalotomy so that institutionalization is no longer considered. Depression was not permanently improved in the two parkinsonian patients undergoing amygdalotomy. Stereotaxic amygdalotomy is a safe and relatively easy procedure for treatment of a select group of patients who have previously been considered untreatable.

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