Cooperativity in O2 binding to iron porphyrins.
- 1 March 1978
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 75 (3) , 1052-1055
- https://doi.org/10.1073/pnas.75.3.1052
Abstract
The solid-gas O2 binding equilibrium was studied for ferrous "picket fence" porphyrinates with sterically hindered axial imidazoles. Such systems show significant cooperativity in their binding of O2: at low O2 pressures a low O2 affinity form exists, and at high O2 pressures a higher O2 affinity form develops. Direct analogies are drawn to the cooperativity shown in O2 binding by Hb. These model systems mimic Hb quantitatively.This publication has 11 references indexed in Scilit:
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