Characterization of human CD25+ CD4+ T cells in thymus, cord and adult blood
Open Access
- 29 May 2002
- journal article
- research article
- Published by Wiley in Immunology
- Vol. 106 (2) , 190-199
- https://doi.org/10.1046/j.1365-2567.2002.01412.x
Abstract
CD4+ CD25+ regulatory T cells prevent organ-specific autoimmune diseases in various animal models. We analysed human lymphoid tissues to identify similar CD25+ regulatory T cells. Adult peripheral bl...Keywords
This publication has 46 references indexed in Scilit:
- Regulatory T Cells in AutoimmmunityAnnual Review of Immunology, 2000
- Regulatory T Cells in the Control of Autoimmunity: the Essential Role of Transforming Growth Factor β and Interleukin 4 in the Prevention of Autoimmune Thyroiditis in Rats by Peripheral CD4+CD45RC− Cells and CD4+CD8− ThymocytesThe Journal of Experimental Medicine, 1999
- Purification of cord blood lymphocytesJournal of Immunological Methods, 1996
- Both activated and nonactivated leukocytes from the periphery continuously enter the thymic medulla of adult rats: phenotypes, sources and magnitude of trafficEuropean Journal of Immunology, 1996
- Expression of Cytokine Receptors by Human Cord Blood Lymphocytes: Comparison with Adult Blood LymphocytesPediatric Research, 1995
- The progressive differentiation of primed T cells is associated with an increasing susceptibility to apoptosisEuropean Journal of Immunology, 1994
- Exclusion of circulating T cells from the thymus does not apply in the neonatal period.The Journal of Experimental Medicine, 1993
- CD38: A multi-lineage cell activation molecule with a split personalityInternational Journal of Clinical and Laboratory Research, 1992
- A novel subpopulation of CD45RA+ CD4+ T cells expressing IL-2 receptor α-chain (CD25) and having a functionally transitional nature into memory cellsInternational Immunology, 1991
- Reentry of T cells to the adult thymus is restricted to activated T cells.The Journal of Experimental Medicine, 1991