On the Interaction between Phagocytes and Micro-Organisms

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Abstract
WHEN phagocytic cells ingest and kill micro-organisms, a variety of biochemical responses ensue and exercise specific roles in the major phases of the phagocytic process.1 , 2 For example, the increased production of hydrogen peroxide, linked to an increase in nonmitochondrial oxygen consumption, is part of a potent microbicidal system.2 The absence of this system may be associated with reduced microbicidal activity by phagocytes in vitro and decreased resistance to infection in man. Undoubtedly, many other microbicidal agents and biochemical systems exist in phagocytes, only some of which have been identified.2 Despite an intense investigative effort, almost nothing is known about the . . .

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