Rapid analysis of metabolic stability of dopamine receptor antagonists and detection of their metabolites by liquid chromatography/tandem mass spectrometry
- 11 February 2003
- journal article
- Published by Elsevier in Analytical Biochemistry
- Vol. 313 (2) , 292-300
- https://doi.org/10.1016/s0003-2697(02)00628-0
Abstract
No abstract availableKeywords
This publication has 12 references indexed in Scilit:
- Practical aspects of liquid chromatography/electrospray tandem mass spectrometry for rapid identification of metabolites of a new antifungal agent SYN‐2836 in dog urineRapid Communications in Mass Spectrometry, 2001
- High‐throughput analysis in drug discovery: application of liquid chromatography/ion‐trap mass spectrometry for simultaneous cassette analysis of α‐1a antagonists and their metabolites in mouse plasmaRapid Communications in Mass Spectrometry, 2001
- Rapid assessment of drug metabolism in the drug discovery processEuropean Journal of Pharmaceutical Sciences, 2000
- Simultaneous quantitative cassette analysis of drugs and detection of their metabolites by high performance liquid chromatography/ion trap mass spectrometryRapid Communications in Mass Spectrometry, 2000
- Development of an automated mass spectrometry system for the quantitative analysis of liver microsomal incubation samples: a tool for rapid screening of new compounds for metabolic stabilityRapid Communications in Mass Spectrometry, 1999
- Identification of drug metabolites in biological matrices by intelligent automated liquid chromatography/ tandem mass spectrometryRapid Communications in Mass Spectrometry, 1998
- In vivo pharmacokinetic screening in cassette dosing experiments: the use of on-line prospekt® liquid chromatography/atmospheric pressure chemical ionization tandem mass spectrometry technology in drug discoveryRapid Communications in Mass Spectrometry, 1998
- Atmospheric Pressure Ionization LC/MS/MS Techniques for Drug Disposition StudiesJournal of Pharmaceutical Sciences, 1998
- Application of liquid chromatography–mass spectrometryn analyses to the characterization of novel glyburide metabolites formed in vitroJournal of Chromatography A, 1998
- Prediction of Hepatic Clearance from Microsomes, Hepatocytes, and Liver SlicesDrug Metabolism Reviews, 1997