EFFECTS OF METHOXYFLURANE (PENTHRANE) ANAESTHESIA IN CHILDREN

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Abstract
Some circulatory and respiratory effects of methoxyflurane anaesthesia were studied in ten normal children. Arterial pressure was little altered by this anaesthetic and the changes observed resembled those produced by halothane rather than di-ethyl ether. The degree of respiratory depression during methoxyflurane anaesthesia was intensified by increasing the concentration of the inhaled vapour. There was no tendency to hyperglycaemia, either prior to or during surgery. Ventricular irregularities were not a feature of methoxyflurane anaesthesia, at either normal or elevated end tidal Pco2 levels.

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