Mdm2: The Ups and Downs

This publication has 93 references indexed in Scilit:

• The proliferation of normal human fibroblasts is dependent upon negative regulation of p53 function by mdm2
  Oncogene, 1998
• Molecular characterization of the hdm2-p53 interaction 1 1Edited by J. Karn
  Journal of Molecular Biology, 1997
• The carboxy terminus of p53 mimics the polylysine effect of protein kinase CK2-catalyzed MDM2 phosphorylation
  Oncogene, 1997
• Regulation of p53 stability by Mdm2
  Nature, 1997
• Mdm2 promotes the rapid degradation of p53
  Nature, 1997
• Conservation of structural domains and biochemical activities of the MDM2 protein from Xenopus laevis
  Oncogene, 1997
• The p53-associated protein MDM2 contains a newly characterized zinc-binding domain called the RING finger
  Trends in Biochemical Sciences, 1994
• Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein.
  Genes & Development, 1994
• Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53
  Nature, 1993
• The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
  Cell, 1992