Experimental Arteriosclerosis: Inhibitory Effects of Ascorbic Acid and Inositol
- 1 October 1952
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 81 (1) , 284-286
- https://doi.org/10.3181/00379727-81-19850
Abstract
Epinephrine and thyroxine, injd. daily in rabbits for 15 days, produced a 90% incidence of arteriosclerosis. This was primarily a medial sclerosis and did not involve atheroma. Subcut. injns. of inositol, 3 g./kg. and 6 g./kg./day during the 15 days of epinephrine[long dash]thyroxine admn., did not produce any inhibition of the epinephrine[long dash]thyroxine induced sclerosis. However, ascorbic acid, similarly given, at 3 dosage levels (50, 100, and 500 mg./kg./day), produced a significant inhibition of the epinephrine[long dash]thyroxine sclerosis.Keywords
This publication has 1 reference indexed in Scilit:
- Hormonal Influences on Epinephrine Induced Aortic SclerosisExperimental Biology and Medicine, 1951