Influence of Age and N, N'-Diethylene-N"-Phenethylphosphoramide (PEDP)Upon Nucleic Acid and Ribonuclease Activity in Tumor Tissue.
- 1 December 1962
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 111 (3) , 708-710
- https://doi.org/10.3181/00379727-111-27898
Abstract
Summary As the Walker 256 tumor increased in size and approached maximum development, the ribonuclease activity per gram of tumor or per mg of deoxyribonucleic acid phosphorus (DNA-P) also increased. The slower growing, larger tumor had a markedly decreased ribonucleic acid phosphorus (RNA-P) and protein concentration. Treating the tumor-bearing rat with N, N'-diethylene-N”-phenethylphosphoramide (PEDP) resulted in reduced rate of growth of the tumor, increased ribonuclease activity, and decreased RNA-P.Keywords
This publication has 1 reference indexed in Scilit:
- Ribonucleic acid and ribonuclease activity in developing leavesBiochimica et Biophysica Acta, 1962