XXVI Cholesterol Granuloma

Publisher Website
Google Scholar
Abstract
Cholesterol granuloma was produced in the tympanic cavity of the rabbit following the repeated injections of 1 per cent solution of oxalic acid. Histo-pathological studies of the experimental cholesterol granuloma revealed that it was not a precursor of the cholesteatoma, and was produced in the course of the absorption of the granulation tissue. The cholesteatoma was produced by ingrowth of the squamous epithelium of the external auditory meatus into the middle ear. The ingrowth of the squamous epithelium appears to arise where the epithelium touches with the loose granulation tissue directly but not where the subepithelial connective tissue is compact. This is one of the most important factors responsible for development of the cholesteatoma. Since both cholesteatoma and so-called cholesterol granuloma seem to need the existence of granulation tissues for their appearance, it is no wonder that co-existence of the two conditions is observed.

This publication has 14 references indexed in Scilit: