ALZHEIMER'S DISEASE: Genetic Studies and Transgenic Models
- 1 December 1998
- journal article
- review article
- Published by Annual Reviews in Annual Review of Genetics
- Vol. 32 (1) , 461-493
- https://doi.org/10.1146/annurev.genet.32.1.461
Abstract
▪ Abstract Recent advances in a variety of areas of research, particularly in genetics and in transgenic (Tg)/gene targeting approaches, have had a substantial impact on our understanding of Alzhei...Keywords
This publication has 205 references indexed in Scilit:
- Tau is a candidate gene for chromosome 17 frontotemporal dementiaAnnals of Neurology, 1998
- Increased Aβ 42(43)-plaque deposition in early-onset familial Alzheimer's disease brains with the deletion of exon 9 and the missense point mutation (H163R) in the PS-1 geneNeuroscience Letters, 1997
- Presenilin 1 is required for Notch 1 and Dll1 expression in the paraxial mesodermNature, 1997
- Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease geneNature, 1995
- LDL receptor-related protein, a multifunctional ApoE receptor, binds secreted β-amyloid precursor protein and mediates its degradationCell, 1995
- β-amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activityCell, 1995
- Expression of APP in Brains of Transgenic Mice Containing the Entire Human APP GeneBiochemical and Biophysical Research Communications, 1993
- Learning in inbred mice: Strain-specific abilities across three radial maze problemsBehavior Genetics, 1993
- Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's diseaseNature, 1991
- Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid proteinBiochemical and Biophysical Research Communications, 1984