On connecting large vessels to small. The meaning of Murray's law.
Open Access
- 1 October 1981
- journal article
- research article
- Published by Rockefeller University Press in The Journal of general physiology
- Vol. 78 (4) , 431-453
- https://doi.org/10.1085/jgp.78.4.431
Abstract
A large part of the branching vasculature of the mammalian circulatory and respiratory systems obeys Murray's law, which states that the cube of the radius of a parent vessel equals the sum of the cubes of the radii of the daughters. Where this law is obeyed, a functional relationship exists between vessel radius and volumetric flow, average linear velocity of flow, velocity profile, vessel-wall shear stress, Reynolds number, and pressure gradient in individual vessels. In homogeneous, full-flow sets of vessels, a relation is also established between vessel radius and the conductance, resistance, and cross-sectional area of a full-flow set.This publication has 21 references indexed in Scilit:
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