Development of small peptides recognizing a monosaccharide by combinatorial chemistry
- 7 November 2000
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- No. 23,p. 2295-2296
- https://doi.org/10.1039/b006714h
Abstract
Small peptides selected from a library of 62000 chemically synthesized peptides were able to recognize a monosaccharide specifically and efficiently using both sandwiching and hydrogen bonding interactions, much like sugar-binding proteins (lectins) with the appropriate orientation of amino acid side chains.Keywords
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