LACK OF MUTAGENIC EFFECT OF HALOTHANE OR CHLOROFORM ON CULTURED CELLS USING THE AZAGUANINE TEST SYSTEM
Open Access
- 1 March 1977
- journal article
- research article
- Published by Elsevier in British Journal of Anaesthesia
- Vol. 49 (3) , 207-210
- https://doi.org/10.1093/bja/49.3.207
Abstract
Halothane with and without nitrous oxide and chloroform alone were tested for mutagenic effects at the 8-azaguanine locus on the chromosomes of Chinese hamster lung fibroblast cells in culture. No significant numbers of mutations were found after 24 h exposures to 1–3% of these anaesthetics, or to 75%.nitrous oxide.This publication has 0 references indexed in Scilit: