A SEARCH FOR PROGESTERONE IN HUMAN URINE

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Abstract
The determination of testosterone in urine provides an easier means for the appreciation of androgenicity than plasma analysis. On this basis a search for progesterone in urine was made without success. Progesterone could not be detected by the gas chromatographic method used. This negative result was confirmed when progesterone-4-C14 was injected intravenously and neither radioactive progesterone nor labelled 20[alpha]-hydrogen-pregn-4en-3-one and/or 20[beta]-hydroxy-pregn-4-en-3-one could be detected in the urine.