Magnetic Resonance Imaging Compared With Computed Tomography in Adrenoleukodystrophy
- 1 October 1986
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Pediatrics & Adolescent Medicine
- Vol. 140 (10) , 1001-1003
- https://doi.org/10.1001/archpedi.1986.02140240047024
Abstract
• Adrenoleukodystrophy was diagnosed in two siblings and confirmed by analysis of very-long-chain fatty acids in skin fibroblasts. Both boys had computed tomograms (CTs) and magnetic resonance imaging (MRI) of the brain. In the most severely affected child, the CT and MRI examinations were both abnormal, but in the other child, the CT was mildly abnormal but the MRI was unequivocally abnormal. This suggests that MRI is more sensitive than CT in detecting the acute demyelinating changes of adrenoleukodystrophy and, in conjunction with very-long-chain fatty acid analysis, should be useful in screening unaffected or mildly affected siblings of patients with this disease. (AJDC 1986;140:1001-1003)This publication has 5 references indexed in Scilit:
- Adrenoleukodystrophy ? Its diverse CT appearances and an evolutive or phenotypic variant: The leukodystrophy without adrenal insufficiencyNeuroradiology, 1982
- Atypical Findings in AdrenoleukodystrophyJournal of Computer Assisted Tomography, 1981
- Computed tomographic evaluation of the early phase of adrenoleukodystrophyNeuroradiology, 1979
- AdrenoleukodystrophyActa Neuropathologica, 1978
- CT scanning and diagnosis of adrenoleukodystrophyNeurology, 1977