Effects of intravenous administration of urographic and cholegraphic contrast media on blood pressure and peripheral circulation

Abstract
The administration of adipiodon and sodium acetrizoate in cats caused a moderate fall in blood pressure and had vasodilator properties, even if the peripheral blood flow was little affected when the substances were injected intravenously. The explanation of the pressure fall is discussed. Repeated doses of adipiodon produced diminishing responses, whereas there was no sign of tachyphylaxis after sodium acetrizoate. Sodium diatri-zoate apparently caused no major vascular effects when injected intravenously.