Prenatal Diagnosis and Elective Termination of Neural Tube Defects in Hawaii, 1986–1997
- 28 April 2000
- journal article
- Published by S. Karger AG in Fetal Diagnosis and Therapy
- Vol. 15 (3) , 146-151
- https://doi.org/10.1159/000020994
Abstract
Objective: To determine the influence of various factors on the prenatal diagnosis and elective termination of neural tube defects (NTDs) in Hawaii in 1986–1997. Methods: Data from a birth defects registry were analyzed and included 245 cases. Results: 74% of the cases were prenatally diagnosed and 48% were terminated. Anencephaly was more likely to be prenatally diagnosed and electively terminated than spina bifida or encephalocele. Other factors such as maternal age, race/ethnicity, place of residence, and elevated maternal serum α-fetoprotein influenced the prenatal diagnosis and/or elective termination of NTD-affected pregnancies. However, a given factor may influence prenatal diagnosis and elective termination in different ways. Conclusions: Various diagnostic and demographic factors can influence the prenatal diagnosis and the subsequent termination of NTD-affected pregnancies.Keywords
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