Effects of Vitamin D and Steroid Hormones on the Active Transport of Calcium by the Intestine

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Abstract
ALTHOUGH the physiologic effects of vitamin D and steroid hormones on calcium metabolism have long been recognized, their mechanisms of action remain unclear. During the past few years there has been much interest in defining the biochemical basis for the effects of vitamin D and glucocorticoids on calcium transport across biologic membranes. Although understanding of mechanisms is still incomplete, some of the recent developments in this area are reviewed here.It is generally recognized that glucocorticoid administration may diminish calcium absorption in vivo, and there is a well known clinical antagonism between the effects of steroid hormones and vitamin D. . . .