Klinische Erfahrungen mit Amoxycillin bei der Behandlung chronischer Bronchitiden

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Abstract
100 patients suffering from chronic relapsing inflammatory diseases of the bronchopulmonary system were treated with amoxycillin (BRL 2333) for an average of 20 days. The efficacy of the product was noted and controlled from the clinical, radiographic, bacteriological and cytological aspects. The pathogenic organisms which were cultured from sputum and bronchial secretions belonged mostly to the group of problematic bacteria. Of 97 patients where complete control was possible, all showed a radiological and clinical satisfactory improvement on their original condition. In 59 cases, there was also a bacteriological cure. Cytologically, there was a significant improvement in 67% of the patients, but in 33 patients (of whom 28 had bronchial carcinoma), there was only a little improvement. The tolerance of amoxycillin per os was exceptionally good, and gastrointestinal disturbances were noted in only 2 patients. In the case of 3 patients, therapy had to be discontinued (in 2 cases because of allergy, and in 1 case because of a maculopapular exanthema).

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