The KH domain occurs in a diverse set of RNA‐binding proteins that include the antiterminator NusA and is probably involved in binding to nucleic acid
- 21 June 1993
- journal article
- Published by Wiley in FEBS Letters
- Vol. 324 (3) , 361-366
- https://doi.org/10.1016/0014-5793(93)80152-k
Abstract
New findings are presented for the ~ 50 residue KH motif, a domain recently discovered in RNA-binding proteins. The conserved sequence is ~ 10 residues larger than previously reported. Profile searches have revealed new members of this family, including two, E. coli NusA and human GAP-associated p62 phosphoprotein, for which RNA-binding data exists. A nus A homolog was detected in the RNA polymerase gene complex of six archaebacterial species and may encode an antiterminator. All KH-containing proteins are linked with RNA and the KH motif most probably functions as a nucleic acid binding domain.Keywords
This publication has 36 references indexed in Scilit:
- RNA recognition: towards identifying determinants of specificityPublished by Elsevier ,2002
- Interaction between bacteriophage λ and its Escherichia coli hostCurrent Opinion in Genetics & Development, 1992
- Complete cDNA sequence of chicken vigilin, a novel protein with amplified and evolutionary conserved domainsEuropean Journal of Biochemistry, 1992
- Meiosis-specific RNA splicing in yeastCell, 1991
- RNA-protein interactions in a Nus a-containing Escherichia coli transcription complex paused at an RNA hairpinJournal of Molecular Biology, 1991
- Different specificities of ribonuclease II and polynucleotide phosphorylase in 3′mRNA decayBiochimie, 1991
- Sequence, organization, transcription and evolution of RNA polymerase subunit genes from the archaebacterial extreme halophiles Halobacterium halobium and Halococcus morrhuaeJournal of Molecular Biology, 1989
- Ribosomal protein gene cluster of Halobacterium halobium: nucleotide sequence of the genes coding for S3 and L29 equivalent ribosomal proteinsCanadian Journal of Microbiology, 1989
- Isolation and structural analysis of the Escherichia coli trp leader paused transcription complexJournal of Molecular Biology, 1987
- CABIOS REVIEWBioinformatics, 1985