β-Blockers for heart failure
- 1 May 1994
- journal article
- review article
- Published by Wolters Kluwer Health in Current Opinion in Cardiology
- Vol. 9 (3) , 295-300
- https://doi.org/10.1097/00001573-199405000-00006
Abstract
The hypothesis that the long-term use of beta-blockers improves symptoms, cardiac function, and ejection fraction in patients with heart failure is increasingly being accepted. Multiple small studies have consistently demonstrated favorable outcomes with beta-blocker use, and a large-scale mortality study is now planned. However, important questions remain regarding which patients with heart failure should be treated and the mechanism by which beta-blockade exerts its beneficial effects. These questions undoubtedly need to be answered before physicians will be willing to prescribe these medications, the use of which is so counterintuitive.Keywords
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