Abstract
Cultures ofC. albicanshave been classified into two groups by means of a double diffusion precipitin test employing rabbit antisera and polysaccharide extracts. In the present series it has been found that 75% of cultures belong to group A and 25% to group B, and it is suggested that the higher incidence of group B strains occurring in the sputum of hospital in-patients with chest disease may be the result of reinfection by attenuated forms which persist in the environment.My thanks are due to many colleagues who provided me with the strains ofC. albicans, and to Prof. H. Hare for helpful criticism in the preparation of this paper.

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