Relations of runoff to altitude may be denned for a hydrologically homogeneous region by using a limited number of streamflow records. Mean runoff from ungaged basins in this same region can then be computed on the basis of this derived relation. When these relations of runoff to altitude are applied to small areas, the runoff may be different from that indicated by the relation, because of local differences in geology, precipitation, vegetation, land slopes, and land use. Two methods are described for adjusting the relations for the effects of these variations; one based on a streamflow measurement at miscellaneous sites which is applicable to perennial streams, the other on measurement of two channel parameters which is applicable to either perennial or ephemeral streams.