Nachweis humaner Papillomvirus-(HPV-)Desoxyribonukleinsäure (DNA) in malignen Tumoren des Oropharynx mittels Dot-Blot-Technik*
- 1 August 1991
- journal article
- abstracts
- Published by Georg Thieme Verlag KG in Laryngo-Rhino-Otologie
- Vol. 70 (08) , 441-444
- https://doi.org/10.1055/s-2007-998072
Abstract
A total of 23 malignant oropharyngeal tumours (palate, tongue, tonsils, pharynx) and two lymph node metastases were analysed for presence of papilloma virus DNA. Thirteen (54.5%) of 22 squamous cell cancers of different koilocytosis and grading were found to contain HPV 16/18 DNA. Only 16.6% (4 cases) were positive for HPV 6/11 DNA. There was no detectable HPV-DNA in the lymph node metastases (Table 1). The control biopsies (19) were negative after hybridisation.Keywords
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