Acquired factor VII deficiency associated with pleural liposarcoma
- 1 October 1994
- journal article
- case report
- Published by Wolters Kluwer Health in Blood Coagulation & Fibrinolysis
- Vol. 5 (5) , 833-836
- https://doi.org/10.1097/00001721-199410000-00023
Abstract
Isolated acquired factor VII (FVII) deficiency (0.15 U/ml) was identified in a 30-year-old man with pleural liposarcoma. The patient underwent surgery with continuous FVII concentrate infusion. No anti-FVII antibody or FVII/anti-FVII complex was detected. However, the short half-life and low recovery of FVII after concentrate infusion suggested the presence of an antibody. Whatever the mechanism, this FVII deficiency was related to the presence of the liposarcoma. FVII level normalized during tumour regression and fell again when the liposarcoma relapsed.Keywords
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