DIRECT IMMUNOELECTRON MICROSCOPY OF TRANSMISSIBLE GASTROENTERITIS VIRUS WITH IMMUNOGLOBULIN-G AND IMMUNOGLOBULIN-A AND GUINEA-PIG COMPLEMENT

1 January 1980

journal article
research article

Vol. 41 (1) , 136-139

Abstract

Porcine colostral immunoglobulin (Ig)G and IgA, isolated from transmissible gastroenteritis virus-infected sows, were compared by direct immunoelectron microscopy. It was estimated, using antibodies with a less than a 2-fold difference in virus-neutralizing activity, that IgG was 500 times more efficient than was IgA for coating transmissible gastroenteritis virions. Guinea pig complement enhanced the antibody coating with IgG, but did not increase virus-neutralizing activity of IgG or IgA.

This publication has 2 references indexed in Scilit:

Partial characterization of the principal soluble antigens associated with the coronavirus of transmissible gastroenteritis by complement fixation and immunodiffusion
Infection and Immunity, 1976
Studies on the nature of the neutralization reaction and the competition for neutralizing antibody between components of the virus system of foot-and-mouth disease
Virology, 1962