Calculation of genetic risks in Duchenne muscular dystrophy by geneticists in the United Kingdom.

1 August 1978

journal article
research article
Published by BMJ in Journal of Medical Genetics

Vol. 15 (4) , 249-253
https://doi.org/10.1136/jmg.15.4.249

Abstract

Pedigrees of Duchenne muscular dystrophy were sent to 32 geneticists in the United Kingdom asking for their calculations of genetic risks for female relatives. Only 7 of 18 participants gave correct answers for all pedigrees. The method most used for calculations (the ''Bayesian'' method) was most liable to errors in new situations. An alternative, simpler method is presented.

Keywords

This publication has 8 references indexed in Scilit:

Genetic Counselling
Published by Elsevier ,1976
A simple combinatorial method for calculating genetic risks
Clinical Genetics, 1975
The Application of Bayesian Methods in Genetic Counselling
Human Heredity, 1969
Genetic Counselling in Lethal X-Linked Disorders
Human Heredity, 1968
Creatine Kinase Levels in Women who Carry Genes for Three Types of Muscular Dystrophy
BMJ, 1965
FORMAL GENETICS OF MUSCULAR DYSTROPHY
1959
HEREDITY COUNSELLING FOR SEX‐LINKED RECESSIVE DEFICIENCY DISEASES
Annals of Human Genetics, 1957
The rate of spontaneous mutation of a human gene
Journal of Genetics, 1935