The use of sildenafil citrate for treatment of male infertility in males with erectile dysfunction

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Abstract
Objectives: Sildenafil Citrate (Viagra) has been shown to be an effective treatment for erectile dysfunction (ED), resulting in erection and subsequent ejaculation. The objective of this study was to evaluate the quantitative and qualitative characteristics of ejaculates in men of reproductive age with ED undergoing infertility evaluation and employment of intrauterine insemination (IUI) for their wives. Materials and methods: A total of 3 patients with ED received Viagra and produced a total of 18 ejaculates for evaluation and sperm preparation for IUI. Each ejaculate was produced at intercourse via the use of the Male Factor Pak. Seminal specimens were assessed and processed via the ZSC-II method for IUI. Each processed specimen was evaluated for its appropriateness for IUI. Results: Sperm quantitative and qualitative measurements after production at intercourse were within normal range (WHO standards), and when specimens were processed for IUI, the sperm quantity and quality were adequate to cause conception. IUI specimens (0.7 mL) contained 23.5 ± 7.1 × 106 sperm/mL with 73.6 ± 6.8% motility and 3.3 ± 0.2 progressive motility (scale of 0–4). Conclusions: It appears that Viagra can be an effective tool for the treatment of reproductive age ED males undergoing infertility treatment in an IUI program. The ejaculates produced and the processed specimens for IUI were of adequate quality to establish a pregnancy in the treated couples.

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