Trisomy 16p in a liveborn offspring due to maternal translocation t(16;21)(q11;p11) and review of the literature

7 June 1992

journal article
case report
Published by Wiley in American Journal of Medical Genetics

Vol. 43 (3) , 621-625
https://doi.org/10.1002/ajmg.1320430324

Abstract

We report on a case of dup(16p) and review previous cases. The triplicated chromosome region leading to this specific syndrome lies in 16p13.1 p13.3. Most of the cases are inherited and the mode of segregation was found to be 3:1 in half of the cases, but these observations might be due to biases. The other chromosomes involved in the translocations as well as the breakpoints in these chromosomes do not appear to be random.

Keywords

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