Synthesis and nuclease susceptibility of alpha-oligodeoxyribonucleotide phosphorothioate.

  • 1 January 1991
    • journal article
    • No. 25,p. 101-2
Abstract
Novel DNA analog, alpha-2'-deoxyoligothymidylate phosphorothioate was conveniently synthesized via phosphoramidite solid support method. The non natural DNA analog showed enhanced stability toward enzymatic degradation.

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