Mechanism of inhibition of 3α,20β-hydroxysteroid dehydrogenaseby a licorice-derived steroidal inhibitor
- 31 October 1994
- Vol. 2 (10) , 973-980
- https://doi.org/10.1016/s0969-2126(94)00099-9
Abstract
No abstract availableKeywords
This publication has 17 references indexed in Scilit:
- The refined three-dimensional structure of 3α,20β-hydroxysteroid dehydrogenase and possible roles of the residues conserved in short-chain dehydrogenasesStructure, 1994
- Site-specific mutagenesis of Drosophila alcohol dehydrogenase: Evidence for involvement of tyrosine-152 and lysine-156 in catalysisBiochemistry, 1993
- Tyr-179 and Lys-183 are essential for enzymatic activity of 11β-hydroxysteroid dehydrogenaseBiochemical and Biophysical Research Communications, 1992
- Protein engineering of Drosophila alcohol dehydrogenase The hydroxyl group of Tyr152 is involved in the active site of the enzymeFEBS Letters, 1992
- Crystal structure of rat liver dihydropteridine reductase.Proceedings of the National Academy of Sciences, 1992
- Three-dimensional structure of holo 3 alpha,20 beta-hydroxysteroid dehydrogenase: a member of a short-chain dehydrogenase family.Proceedings of the National Academy of Sciences, 1991
- Site-directed mutagenesis of the conserved tyrosine 151 of human placental NAD+-dependent 15-hydroxyprostaglandin dehydrogenase yields a catalytically inactive enzymeBiochemical and Biophysical Research Communications, 1991
- Bifunctional enzyme activity at the same active site: study of 3.alpha. and 20.beta. activity by affinity alkylation of 3.alpha.,20.beta.-hydroxysteroid dehydrogenase with 17-(bromoacetoxy)steroidsBiochemistry, 1980
- Effect of carbenoxolone on prostaglandin synthesis and degradationJournal of Pharmacy and Pharmacology, 1976
- Structural Features of Ring A and the Interaction of 20‐Oxosteroids with Cortisone ReductaseEuropean Journal of Biochemistry, 1972