Preventing Coronary Restenosis and Complications

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Abstract
Interventions aimed at opening occluded coronary arteries continue to evolve. Two fundamental problems that limit the clinical efficacy of coronary interventions are restenosis after coronary angioplasty or atherectomy,13 reported since the early days of interventional cardiology, and acute complications from the intervention, such as coronary-artery dissection, acute or threatened vessel closure, and distal embolization.4,5 Both problems are the result of injury to the arterial wall. Attempts at solving these problems have involved the development of new devices and drugs. Two of the most promising solutions are described in this issue of the Journal.6,7 Preventing RestenosisDespite . . .