4-Alkoxy-3-cyano-2(1H)-pyridones and 5-Alkoxyisoxazoles and Their Aryl Substituted and Annulated Derivatives from Acylketene O,S-Acetals
- 1 June 1995
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1995 (06) , 641-643
- https://doi.org/10.1055/s-1995-3974
Abstract
The title pyridones 2 and 5 and the isoxazoles 3 are obtained in moderate to good yields by cyclocondensation of the appropriate acylketene O,S-acetals 1 or 4 with cyanoacetamide and hydroxylamine hydrochloride, respectively, in the presence of sodium alkoxide/alkanol.Keywords
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