Effect of Chromatotrophic Hormone on Pigments of Anuran Skin.

Abstract
Previous reports have indicated that the deposition of melanin in amphibian skin is under the influence of CTH, the chromatotrophic hormone. Also, inferences have been made that the quantity of other pigments of the skin, especially guanine is dependent upon CTH. In the present experiments, extracts of skins of Rana plpiens or Rana sylvatlca were studied by means of paper chromatography. Skins were taken from adult frogs as well as normal, hypophysioprivic, and CTH-treated hypo-physioprivic larvae. The hypophysis exerts both quantitative and qualitative effects on both guanine and the pterins of the skin.

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