Plasma alpha 1‐acid glycoprotein concentration in broilers: Influence of age, sex and injection ofescherichia colilipopolysaccharide

Abstract
1. The influence of age, sex and injection of Escherichia coli lipopolysaccharide (LPS) on the plasma concentration of alpha‐1 acid glycoprotein (AGP) was determined in broilers using the single radial immunodiffusion method. 2. Plasma AGP concentration increased in the 3 d after hatching, and then stabilised at 240 ± 33 μg/ml up to 14 d of age. 3. No sex‐related differences in plasma AGP concentration were observed up to 6 weeks of age. 4. A single injection of 900 μg LPS per chick resulted in a 5‐fold increase in AGP concentration compared with that in saline‐injected chicks. Multiple injections of LPS (200 μg/chick every 2d for 14d) caused only a 50% increase in AGP concentration.

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