The role of manganese superoxide dismutase in health and disease
- 1 August 1998
- journal article
- review article
- Published by Wiley in Journal of Inherited Metabolic Disease
- Vol. 21 (5) , 598-603
- https://doi.org/10.1023/a:1005427323835
Abstract
Manganese superoxide dismutase (MnSOD) is the mitochondrial enzyme that disposes of superoxide generated by respiratory chain activity. Of all electrons passing down the mitochondrial respiratory cha...Keywords
This publication has 25 references indexed in Scilit:
- Excessive formation of hydroxyl radicals and aldehydic lipid peroxidation products in cultured skin fibroblasts from patients with complex I deficiency.Journal of Clinical Investigation, 1997
- NADH‐coenzyme Q reductase (complex I) deficiency: heterogeneity in phenotype and biochemical findingsJournal of Inherited Metabolic Disease, 1996
- Expression ofBCL-2Inhibits Cellular Radical GenerationFree Radical Research, 1996
- Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutaseNature Genetics, 1995
- SUPEROXIDE RADICAL AND SUPEROXIDE DISMUTASESAnnual Review of Biochemistry, 1995
- Molecular Structure and Organization of the Human Manganese Superoxide Dismutase GeneDNA and Cell Biology, 1994
- Inherited Enhancement of Hydroxyl Radical Generation and Lipid Peroxidation in the S Strain Rats Results in DNA Rearrangements, Degenerative Diseases, and Premature AgingBiochemical and Biophysical Research Communications, 1994
- Mitochondrial respiratory chain inhibitors induce apoptosisFEBS Letters, 1994
- Bcl-2 functions in an antioxidant pathway to prevent apoptosisCell, 1993
- The structure of human mitochondrial manganese superoxide dismutase reveals a novel tetrameric interface of two 4-helix bundlesCell, 1992