In the course of experiments already published on the origin from the spinal cord of the sweat-fibres for the fore-foot, and of the pilo-motor fibres for the face and neck, I had occasion to stimulate, in the spinal canal, the lower cervical and upper thoracic nerves. Whilst doing so I paid attention to the occurrence or non-occurrence of effects other than those with which I was at the time most concerned. Since the resuffs were in many cases not in accordance with the statements of earlier observers, it seemed to me desirable to determine as many as possible of the “sympathetic” effects, which can be produced by stimulation of each of the lower cervical and of the upper thoracic nerves.