Studies in the Solid Phase Synthesis of Oligo- and Poly-Ribonucleotides
- 1 January 1991
- journal article
- plenary lectures
- Published by Taylor & Francis in Nucleosides and Nucleotides
- Vol. 10 (1) , 81-97
- https://doi.org/10.1080/07328319108046437
Abstract
The solid phase synthesis of the 3′-terminal 10-mer, 19-mer and 37-mer sequences of unmodified yeast tRNAAla is described. The 2′- and 5′-hydroxy functions are protected, respectively, by the 1- (2-fluorophenyl)-4-methoxypiperidin-4-yl [Fpmp (11)] and 9-phenylxan-then-9-yl [px] groups, and 2-cyanoethyl di-isopropylphosphoramidite building blocks are used.Keywords
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