In vitro PHOTOSENSITIZATION WITH A BENZOPORPHYRIN DERIVATIVE
- 1 May 1989
- journal article
- research article
- Published by Wiley in Photochemistry and Photobiology
- Vol. 49 (5) , 579-582
- https://doi.org/10.1111/j.1751-1097.1989.tb08426.x
Abstract
Biophysical and photobiological properties of two benzoporphyrin derivatives were examined. These dyes exhibit substantial absorbance in the red, and are potent photosensitizers in vitro. After brief (0.5 h) incubations, phototoxicity was more closely correlated with membrane than with mitochondrial photodamage. Affinity of these dyes toward plasma lipoproteins are consistent with a mode of localization via the LDL-mediated mechanism utilized by the hematoporphyrin-derived product, HPD.This publication has 15 references indexed in Scilit:
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