T4 gene 32 protein model for control of activity at replication fork
- 1 February 1976
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 259 (5543) , 455-458
- https://doi.org/10.1038/259455a0
Abstract
Limited hydrolysis of gene 32 protein [of bacteriophage T4] by various proteinases results in the production of 3 stable cleavage products. Two of these products show an affinity for native T4 DNA cellulose that the uncleaved protein does not exhibit. A model for proteolytic cleavage and for the local unwinding of DNA in advance of the replication fork is discussed in terms of this unusual binding affinity.Keywords
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