Calcifications in the Prostate Gland and Adjacent Tissues

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Abstract
In 103 autopsies a correlated microradiological and histological examination was performed on the prostate glands with the surrounding venous plexus and on the seminal vesicles with the most proximal 2 cm of the spermatic cord. Four main types of calcifications were found (I) rounded, generally multiple, moderately radiopaque calcifications in the prostate, (II) large, rounded, solitary, strongly radiopaque calcifications in the periprostatic venous plexus, (III) arterial calcifications, and (TV) calcifications in the adventitia and muscular coat of the seminal vesicles and the spermatic cords, resembling media calcifications in arteries. The first 2 types were much more common than the last 2. Type (II) was more commonly observed in the cases with marked fibromyoglandular hyperplasia than in those without. Well-developed calcifications of type (IV) occurred only in a 44-year-old man who died of miliary tuberculosis. The X-ray diffraction examination showed that the rounded calcifications in the prostate gland contained a mixture of tricalcium phosphate and calcium hydroxyapatite.

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