Stereoselective Synthesis of 2‘-C-Methyl-cyclopropyl-Fused Carbanucleosides as Potential Anti-HCV Agents
- 29 September 2006
- journal article
- research article
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 8 (22) , 5081-5083
- https://doi.org/10.1021/ol061959f
Abstract
Stereoselective synthesis of 2‘-C-methyl-cyclopropyl-fused carbanucleosides was accomplished via stereoselective cyclopropanation, regioselective cleavage of the isopropylidene group, stereoselective Grignard reaction, and cyclic sulfate chemistry.Keywords
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